An award-winning innovator and disruptor, Reggie Fils-Aimé is a proven expert on transforming companies, re-vitalizing brands, and reshaping industries to solve daunting challenges and achieve ‘the impossible.’ Most recently, he was the president and chief operating officer of Nintendo of America – the first American and African-American to hold this position. Revered by business leaders and gaming fans alike, Fils-Aimé helped bring Nintendo’s greatest successes – including the Nintendo DS, the Wii, the Nintendo 3DS, Wii U, and the Nintendo Switch – to the global marketplace. Using his personal story as an example, he shares with audiences his principles for effective and innovative leadership, including defining a vision, courage in decision-making, and “irrefutable integrity.”

Described as America’s most widely recognized medical expert after Dr. Anthony Fauci, Dr. Vin Gupta, MD, MPA is a tech visionary who operates at the heart of disruption to develop solutions to the most-complex challenges in commerce, communication, healthcare, and society — now, and in the future. Close to two decades of experience as a renowned health policy expert and clinician have led Dr. Gupta to his current role as chief medical officer, Amazon Pharmacy, where he spearheads cutting-edge programs that are leading us into the interdependent futures of healthcare and technology. A uniquely public-facing figure keeping the world in the know about what’s happening now and next, Dr. Gupta’s forward-looking insights inspire leaders and their organizations to embrace change, think outside the box to break new ground, and create new inroads to innovation and success.

Ramez Naam is a former Microsoft executive, entrepreneur, inventor, and the Energy Co-Chair at Singularity University. Ramez spent 13 years at Microsoft, where he led teams working on artificial intelligence, big data, and internet search. His software has touched the lives of more than a billion people. He holds more than 20 patents—including several as co-inventor with Bill Gates. Dynamic and personable, Naam speaks around the world, captivating audiences as he illustrates “what disruption looks like” and shares the eight strategies incumbents should draw on to keep the pace of change.