With a medical, scientific, and philanthropic career that spans more than 30 years, Dr. Sue Desmond-Hellmann has devoted her life to improving the human condition through innovation. Most recently, she was the CEO of the Bill & Melinda Gates Foundation, leading the organization’s vision for a world where every person has the opportunity to live a healthy, productive life. She was formerly the first female chancellor of University of California at San Francisco and spent 14 years at biotech firm Genentech, leading the development of a number of breakthrough medicines. An innovator and leader in life sciences, Dr. Desmond-Hellmann’s diverse training as an oncologist, scientist, and business executive leads to her endless curiosity about the world and her desire to change it for the better. In speeches, she shares her unique insights not only on revolutionizing global health, but also on effective and innovative leadership. Using lessons-learned as a trailblazing female leader of one of the world’s largest philanthropies, Dr. Desmond-Hellmann inspires audiences with her unparalleled perspective on how to foster an environment of collaboration and relentless innovation to drive disruptive solutions that make an impact.

Mick Ebeling is an American film, television and commercial executive producer as well as an author, entrepreneur and philanthropist. He was named as on one of the Top 50 Most Creative People of 2014, won the SXSW Innovation Award twice in a row (2014 and 2015), and was awarded the 2014 Muhammed Ali Humanitarian of the Year Award. He is the CEO of Not Impossible, an organization that develops creative technology solutions to address real-world problems.

A school teacher turned actor, musician, two-time national poetry slam champion, entrepreneur, and award-winning poetic voice, any given day may now find Sekou keynoting at a leadership conference, helping a Fortune 500 company with brand messaging, or even performing pieces for Barack Obama in Oprah’s backyard. Sekou is the creator of Poetic Voice, a new, cutting-edge speaking category that seamlessly fuses inspirational speaking with spoken word poetry to make messages more moving and memorable. For over 15 years, Sekou Andrews has been helping the world’s largest organizations deliver relevant information with riveting inspiration through an innovative, unconventional category of speaking called “Poetic Voice.”

A powerhouse presence in the world’s most famous kitchens and as a mental health and wellness advocate, Andre Rush is a celebrity chef and decorated U.S. Army combat veteran with more than 20 years of service. Renowned as the White House Chef with 24-inch biceps, Chef Rush served through the administrations of Presidents Clinton, Bush, Obama, and Trump, gaining international attention for his unmistakable muscular physique when a picture of him preparing a meal on the White House lawn went viral and received more than one hundred million views. He uses his platform to advocate on behalf of our nation’s veterans, while also sharing important messages about wellness, individual and collective growth, and the moments that shape who we are.

John Ondrasik, better known by his stage name Five for Fighting, is a platinum-selling, Grammy nominated American singer-songwriter who has released six major albums and sold more than 2.5 million records and whose hits include “100 Years,” “Superman (It’s Not Easy),” “Chances,” “The Riddle,” “Freedom Never Cries,” and “What If.” Ondrasik offers audiences an intimate evening of storytelling, humor, and great music. He offers insights on the creative process and innovation while sharing stories and playing his most famous songs.

A first-generation American immigrant, turned American soldier, combat veteran, and now a professional touring stand-up comedian, Thom Tran turned a literal lifetime of war and tragedy into a successful comedy career. On 3 April 2003, his 4th day in Iraq, during a gunfight Thom was struck in the back of the head by a sniper’s bullet. On April 3, 2003, his 4th day in Iraq, during a gunfight Thom was struck in the back of the head by a sniper’s bullet. Since starting his comedy career, Thom created the GIs of Comedy tour, a group of combat veterans turned stand-up comedians.

As an internationally recognized graffiti artist, author and entrepreneur, Erik redefines the term “keynote speaker.” Pulling from his history as both a businessman and an artist, he has grown to become one of the most sought-after corporate speakers available today. Erik’s on-stage painting seamlessly becomes a visual metaphor to the core of his message, encouraging organizations toward profitability through innovations and superior levels of performance. His list of clients includes AT&T, Disney, London School of Business, Microsoft, FedEx, Exxon Mobil, Ernst & Young, and XPrize; Erik has even been featured as a TED presenter. The responses received have been nothing short of incredible, with standing ovations to prove it.

A unique sense of humor and profound dry wit separates Kevin Nealon from other performers. A likable comedian, he got his start as a department store Santa Claus. Now the longest-running cast member of Saturday Night Live, Nealon's familiar face appears in movies such as Happy Gilmore and The Wedding Singer.

Dana Carvey is an American actor and stand-up comedian best known for his work as a cast member on Saturday Night Live. He is also known for playing the role of Garth Algar in the Wayne's World movies. A sidesplitting addition to any audience, Carvey is one of America's most notable comedians.

An actor, comedian, sports commentator, and Emmy Award-winner, Dennis Miller is known as for his voice behind the desk of Saturday Night Live's "Weekend Update" and as the former host of his own television talk show. A recognizable face in comedy and film, Miller's brilliant stand-up, razor-sharp wit, and his creative rants result in edgy hilarity and lively audiences.

“As Long As You’re Asking – A Conversation with Jason Alexander” is an evening of comedy, music, and conversation with the award-winning star of stage and screen in which the audience determines what they want to know the most. Alexander will present a variety of topics for the audience to pick and choose, culminating in behind the scenes stories of his life, career, and social activism. Or ask about anything you’ve always wanted to know and see if he can answer. Alexander has starred on Broadway, in hit films like Pretty Woman and Shallow Hal and, of course, Seinfeld. He is an actor, director, producer, writer, children’s book author, award-winning magician, semi-pro poker player and social/political activist. It’s all on the table and the conversation is completely in your control, making for a once in a lifetime event.

For 28 years, comedian Kathleen Madigan has been touring 250 nights on the road and squeezing in hour-long filmed specials and performances on every late night show ever made. From 25 appearances on "The Tonight Show" and multiple appearances on Letterman and Conan to recently riding around with Jerry Seinfeld in his internet series "Comedians in Cars Getting Coffee," Madigan is still having a blast and selling out theaters across the country. She's won the American Comedy Award for "Best Female Comedian" and the Phyllis Diller award for "Best Female Comedian." She has written and produced for Lewis Black's "Root of All Evil" on Comedy Central and done multiple USO tours in Iraq and Afghanistan.