With a medical, scientific, and philanthropic career that spans more than 30 years, Dr. Sue Desmond-Hellmann has devoted her life to improving the human condition through innovation. Most recently, she was the CEO of the Bill & Melinda Gates Foundation, leading the organization’s vision for a world where every person has the opportunity to live a healthy, productive life. She was formerly the first female chancellor of University of California at San Francisco and spent 14 years at biotech firm Genentech, leading the development of a number of breakthrough medicines. An innovator and leader in life sciences, Dr. Desmond-Hellmann’s diverse training as an oncologist, scientist, and business executive leads to her endless curiosity about the world and her desire to change it for the better. In speeches, she shares her unique insights not only on revolutionizing global health, but also on effective and innovative leadership. Using lessons-learned as a trailblazing female leader of one of the world’s largest philanthropies, Dr. Desmond-Hellmann inspires audiences with her unparalleled perspective on how to foster an environment of collaboration and relentless innovation to drive disruptive solutions that make an impact.

Michael (Mike) Steep is the founder and former executive director of Stanford Engineering School's Center for Disruptive Technology and Digital Cities and the former senior vice president of global business operations at innovation mega-hub, PARC Xerox. He draws on first-hand experience and anecdotes from time spent with the biggest names in Silicon Valley to instruct audiences on how to get ahead of disruptive innovation. Viewing new technology as opportunity, Mike highlights the importance of allowing innovation to trump company culture and legacies—and not the other way around.

Part journalist, part historian, and all shrewd political observer, Ronald (Ron) Brownstein explains the complexities of American politics with lucid precision. As a CNN Senior Political Analyst, Senior Editor for the Atlantic, and Contributing Editor for National Journal, he produces sharp analysis on politics, policy, the electorate, media, healthcare, energy, the press' impact on Americans, and the range of issues informed by his strong sense of American political and national history. Brownstein provides an insider’s look into politics and the media and has twice been a finalist for the Pulitzer Prize. He is also the author of seven best-selling books, and his articles on politics, public policy, and culture have appeared in myriad of major publications and on many broadcast news outlets.

Amy Holmes is a familiar face with an unconventional voice in political news. As an on-air political analyst, Amy dissects and debates the issues of the day, appearing regularly on CNN, MSNBC, Fox News and PBS. She is the host of the PBS weekly program "In Principle," and the former host of the daily MSNBC morning show Way Too Early. In addition to working with TheBlaze and MSNBC, she co-hosted the Washington Times and Talk Radio Network's America’s Morning News, a nationally-syndicated morning radio show heard coast-to-coast by over 1.5 million listeners daily.

Gianno Caldwell is founder and principal at Caldwell Strategic Consulting—a bipartisan firm headquartered in Washington, DC, which provides strategic advice and consulting in the areas of Public Affairs and Government Relations. Gianno has held a role on behalf of a member of Congress as well as roles at the federal, state, and local level reflecting over 15 years of total experience and seven years of legislative experience culminating in the recognition of his ability to effectively create legislative strategies and build bipartisan coalitions. He is a Fox News Political Analyst who frequently provides analysis and commentary on political, financial, and cultural issues. He's also a contributor to the Hill Newspaper. His opinions are sought out on a wide variety of topics, including domestic policy, the economy, and Congress. In addition, Gianno is Porsche Power 30 under 30 as well as Red Alert Politics 30 under 30 award recipient for 2016.

Leading financial expert and popular author, Todd Buchholz is an economist and has served as White House director of economic policy under George H.W. Bush and a managing director of the Tiger hedge fund. As a frequent commentator on the state of the markets, Todd Buchholz brings his experience as a former White House director of economic policy, a managing director of the $15 billion Tiger hedge fund, and a Harvard economics teacher to the cutting edge of economics, fiscal politics, finance, and business strategy.

Lanhee J. Chen, Ph.D. is a research fellow at the Hoover Institution and teaches in the Public Policy Program at Stanford University. His current research focuses on campaigns and elections, health policy, economic policy, and California policy and politics. Chen, a veteran of several high-profile political campaigns, has also served in government, the private sector, and academia. Dr. Chen also served as Governor Romney’s chief policy adviser, a senior strategist on the campaign, and the person responsible for developing the campaign’s domestic and foreign policy.

Jeffrey Pfeffer is the Thomas D. Dee II Professor of Organizational Behavior in the Graduate School of Business at Stanford University, where he has taught since 1979. He has been published extensively in the fields of organization theory and human resource management.

Tony Seba is a world-renowned thought leader, author, speaker, educator, angel investor and Silicon Valley entrepreneur. Tony is the author of the #1 Amazon best-selling book“Clean Disruption of Energy and Transportation” and co-author of “Rethinking Humanity”. Tony’s work focuses on the science of change, disruption and transformation, which includes cost-curves, S-curves, convergence and complex systems and has been used to accurately predict the ongoing phase change disruptions of transportation, energy, food & agriculture, information, as well as implications for society and geopolitics. Tony holds a Stanford MBA and a B.S. in Computer Science & Engineering from MIT.

Bea Johnson and her family are dedicated to living a Zero Waste lifestyle; they generate a mere quart of waste per year. Through her blog and with her book, Zero Waste Home, Bea inspires a growing international community to live simply and take a stance against needless waste. Her passion and positive outlook have earned her appearances on TV and in publications around the world. Grand prize winner of "The Green Awards" in 2011, she regularly speaks at universities, corporate events and conferences. She has become the spokesperson for the Zero Waste lifestyle or, as The New York Times puts it: “The Waste-Free Priestess”.

Reflecting his interdisciplinary training in American Studies, which combined the fields of history, literature, and economics, Professor Kennedy's scholarship is notable for its integration of economic and cultural analysis with social and political history. His 1970 book, Birth Control in America: The Career of Margaret Sanger, embraced the medical, legal, political, and religious dimensions of the subject and helped to pioneer the emerging field of women's history. Over Here: The First World War and American Society (1980) used the history of American involvement in World War I to analyze the American political system, economy, and culture in the early twentieth century. Freedom From Fear: The American People in Depression and War (1999) recounts the history of the United States in the two great crises of the Great Depression and World War II.