With a medical, scientific, and philanthropic career that spans more than 30 years, Dr. Sue Desmond-Hellmann has devoted her life to improving the human condition through innovation. Most recently, she was the CEO of the Bill & Melinda Gates Foundation, leading the organization’s vision for a world where every person has the opportunity to live a healthy, productive life. She was formerly the first female chancellor of University of California at San Francisco and spent 14 years at biotech firm Genentech, leading the development of a number of breakthrough medicines. An innovator and leader in life sciences, Dr. Desmond-Hellmann’s diverse training as an oncologist, scientist, and business executive leads to her endless curiosity about the world and her desire to change it for the better. In speeches, she shares her unique insights not only on revolutionizing global health, but also on effective and innovative leadership. Using lessons-learned as a trailblazing female leader of one of the world’s largest philanthropies, Dr. Desmond-Hellmann inspires audiences with her unparalleled perspective on how to foster an environment of collaboration and relentless innovation to drive disruptive solutions that make an impact.

Indu Subaiya is a visionary healthcare leader whose work builds community, creates dialogue and inspires us to radically rethink how health shapes our lives. Indu is Co-founder and President of Catalyst @ Health 2.0, the industry leader in digital health strategic partnering, innovation competitions and programs for piloting and commercializing novel healthcare technologies. In 2007, Indu co-founded and served as CEO of Health 2.0, a global conference platform and community for the showcase and advancement of new technologies in healthcare. Health 2.0's conference business was acquired by HIMSS in 2017 and in the two years post acquisition, Indu headed the organization as Executive Vice President. She continues as Senior Advisor to HIMSS, providing thought leadership and content advisory services under the office of the Chief Technology and Innovation Officer. In 2013, FierceHealthIT named Indu one of Health Information Technology’s Most Influential Women. In 2018, Indu was selected as a fellow of the Aspen Institute's fourth class of Health Innovators Fellows.

A 21-year veteran of the United States Air Force, Colonel Nicole Malachowski (USAF, Ret.) wanted to fly military jets from the moment she saw them at her first air show when she was five years old. She achieved that goal – and then some. A leader, a combat veteran, the first woman pilot on the Thunderbirds Air Demonstration Squadron, an instructor, a White House Fellow, and an inductee into the Women in Aviation International Pioneer Hall of Fame, Nicole’s Air Force career exceeded her wildest dreams.

Laila Ali is a world-class athlete, fitness & nutrition expert, TV host, cooking enthusiast, founder of the Laila Ali Lifestyle Brand and mother of two. The daughter of late beloved global icon and humanitarian, Muhammad Ali, she is a four-time undefeated boxing world champion, whose stellar record includes 24 wins (21 of which were "knockouts") and zero losses. Laila is heralded as the most successful female in the history of women’s boxing.

An adventurer, record-setter, and boundary-breaker, Darcy Gaechter is best known as the first woman - and member of the first team - to kayak the Amazon River from source to sea. The journey required her crew to paddle over 4,000 miles across the widest part of South America, a voyage that took 148 days to complete. She is also the author of The Kayaker’s Guide to Ecuador and Amazon Woman, an adventure memoir detailing her Amazon River expedition and the life challenges she faced to get there – the rights of which have been purchased to turn her story into a movie. Gaechter inspires audiences with her personal journey of overcoming obstacles and making the impossible possible – sharing useful tactics to take on even the most daunting of challenges and demonstrating how a strong belief in yourself and in your goal are key ingredients to any success.

Jane Chen is the co-founder and CEO of Embrace, a social enterprise that aims to help the 15 million premature and low birth-weight babies born every year, through a low-cost infant warmer. The Embrace infant warmer costs about 1% of a traditional incubator and is estimated to have helped over 250,000 babies to date. Most recently, Embrace Innovations launched a new line of baby products for the US market called Little Lotus Baby, which uses NASA inspired technology to keep babies at the perfect temperature so they can sleep better. They are using buy-one, give-one model: for every product sold, a baby is helped in a developing country by the Embrace infant warmer.

At 22 years old, Lauren Simmons shattered the glass ceiling and made history by being the youngest and only full-time female equity trader on Wall Street for Rosenblatt Securities. Affectionately called the “Wolfette of Wall Street,” Simmons was also the second African American woman in history to hold the prestigious title. Since Lauren’s departure from the trading floor, she is now a multifaceted entrepreneur, an author, personal finance expert, global motivational speaker, producer, and director. She was also named to Harper’s Bazaar’s “Woman Who Dare” 2019 list. Currently, Simmons is executive producing a biopic of her life story with AGC studio – starring Kiersey Clemons and scheduled to release in summer 2021. Additionally, Lauren is the host of Going Public a new financial tv series on Entrepreneur.com coming out spring 2021.

Amy Purdy had a typical childhood until losing her legs at 19 as a result of Meningitis, which has led to an adulthood of extraordinary accomplishments. Amy is the top ranked adaptive snowboarder in the US, a three-time World Cup Para-Snowboard winner, the 2014 Paralympic Bronze Medalist, and the 2018 Paralympic Silver Medalist. She is the co-founder of Adaptive Action Sports (AAS), a non-profit organization which helps disabled youth, young adults, and wounded veterans get involved with action sports, and the author of the New York Times best-selling book, On My Own Two Feet. Amy has evolved into a powerful inspirational and motivational speaker who has been seen by millions of people and invited to share her story to audiences around the world.

Debbie Sterling is the Founder and CEO of GoldieBlox, an award winning company on a mission to ‐"disrupt the pink aisle" with toys, games, and media for girls. Debbie is an engineer, entrepreneur, and one of the leaders in the movement toward getting girls interested in science, technology, engineering, and math. She was named TIME Magazine’s "Person of the Moment,” Business Insider’s "30 Women Who Are Changing the World,” and was recently added to Fortune Magazine’s prestigious “40 Under 40” list. In early 2015, Debbie was inducted as a Presidential Ambassador for Global Entrepreneurship and honored by the National Women’s History Museum with a “Living Legacy” Award for her work to empower girls around the world.

Patricia Wilson is the Former CEO of Make-A-Wish, Greater Bay Area. As one of the nation’s largest Make-A-Wish chapters, it grants more than 400 wishes per year for children with life-threatening medical conditions in northern California. She is best-known as the mastermind behind the incredible effort to turn San Francisco into Gotham City so that cancer patient Miles could become Batkid for a day. A popular TED speaker, Wilson is sought-after for her inspirational insights on leadership, philanthropy, social media, and public relations.

Melissa Stockwell is an American war hero who has triumphed over personal tragedy to achieve greatness, World Champion status, and she has dedicated her life to chasing remarkable accomplishments while giving back to others, particularly those who face challenges similar to her own.

Klyn was born with the life threatening genetic disease, Cystic Fibrosis. Over the years, she has battled the disease as well as big pharma to lower the price of a life saving drug. She reminds us all to live authentically, love deeply, and to recognize adversity as an advantage. After all, “Life isn’t measured by the number of breaths we take, but by the number of moments we create, that take our breath away.”