With a medical, scientific, and philanthropic career that spans more than 30 years, Dr. Sue Desmond-Hellmann has devoted her life to improving the human condition through innovation. Most recently, she was the CEO of the Bill & Melinda Gates Foundation, leading the organization’s vision for a world where every person has the opportunity to live a healthy, productive life. She was formerly the first female chancellor of University of California at San Francisco and spent 14 years at biotech firm Genentech, leading the development of a number of breakthrough medicines. An innovator and leader in life sciences, Dr. Desmond-Hellmann’s diverse training as an oncologist, scientist, and business executive leads to her endless curiosity about the world and her desire to change it for the better. In speeches, she shares her unique insights not only on revolutionizing global health, but also on effective and innovative leadership. Using lessons-learned as a trailblazing female leader of one of the world’s largest philanthropies, Dr. Desmond-Hellmann inspires audiences with her unparalleled perspective on how to foster an environment of collaboration and relentless innovation to drive disruptive solutions that make an impact.

Cassandra “Cassi” Chandler is an innovator, strategist, investigator, and leader who has broken barriers, led diverse teams, and built cultures of motivational leadership and inclusivity at some of the world’s most important organizations, including Bank of America and the FBI. In a career that has included many “firsts” across the U.S. government and financial services industries, she served as the FBI’s first African American female special agent assistant director as well as the Bureau’s first female national spokesperson and director of public and community affairs. In addition to defining the tools motivational leaders need to mindfully build more high-performing cultures, Chandler provides actionable insights on how to move the needle while leading with empathy.

Conservation biologist and National Geographic explorer Steve Boyes gives audiences an eye-opening look at the world around us and shares insights on the power of exploration. Through the use of stunning high-quality images and stories, he challenges audiences to view the world with a fresh perspective. He believes that rich biodiversity is the key to maintaining our quality of life and connection to the planet, and he shares the human experience of the wilderness with audiences so that they come to understand why they need to protect areas that they will likely never see firsthand.

A mission-driven innovator and entrepreneur, Seth Goldman is the founder of Eat the Change, a planet-friendly snack company and platform to inform and empower consumers to make dietary choices aligned with their concerns around climate and health. The first business launched under the Eat the Change umbrella was PLNT Burger, which is a plant-based quick-serve restaurant that offers delicious burgers, sandwiches, fries, and soft-serve. Goldman also serves as chair of the board of Beyond Meat, a publicly traded California-based enterprise on the cutting edge of plant-based protein.

Described as the “Warrior Storyteller,” retired Lieutenant Colonel Scott Mann is a human connection expert and coach who works alongside organizations to unite their teams around a shared vision and arm them with the tools and resources to make an impact and achieve mission success. A former U.S. Army Green Beret who specialized in unconventional, high-impact special operations in do-or-die conflict zones all over the globe, Mann applies his hard-won lessons from the battlefield to business as he shares the relationship-building techniques that drove so many of his successful combat operations. Through Rooftop Leadership, the professional training and coaching program that he founded, Mann advises servant leaders across industries — from Fortune 100 corporations (including Capital One, Walmart, Raymond James, and Fannie Mae) to local small businesses — on how to mobilize their teams, forge deeper connections with their people, and gain a more complete understanding of the opportunities that exist to create high-trust, high-performance cultures.

For more than 12 years, Evy Poumpouras served as a Secret Service special agent in an action-packed career during which she was responsible for protecting the world’s most high-value assets. She was a member of the Presidential Protective Division for President Barack Obama and First Lady Michelle Obama, and also protected Presidents George W. Bush, Bill Clinton, and George H.W. Bush. Today, she is a widely recognized multimedia journalist, host, and producer who uses her skills in front of the camera and behind it to conduct headline-grabbing interviews and investigate the biggest stories in the media. She appears regularly on “TODAY,” NBC, MSNBC, and “Good Morning America” to share her sought-after expertise on national security, law enforcement, and crime, and is the host of Bravo TV’s competition series “Spy Games.” Having mastered the arts of communication and psychology in a wide-ranging career that has taken her from the Secret Service to the TV screen and everywhere in between, Poumpouras offers unconventional strategies for crushing any challenge and living life fearlessly.

Widely respected as an innovator in unlocking high performance in teams and individuals, Dr. Wendy Borlabi possesses expert-level understanding of the mental aspects of peak performance and works alongside the world’s top athletes to help them reframe their mindsets to reach their full potential. She is the director of performance and mental health for the Chicago Bulls where her mindset-centered philosophy to mastering your field is embedded in the team’s success and prevalent at all levels of the organization and its culture. A leading sports psychologists and performance coach, Dr. Borlabi is also an independent consultant with the NBA and is the founder of performance psychology firm Borlabi Consulting, through which she advises organizations in any industry on teamwork, elevating mental toughness, and inspiring unwavering confidence in their teams. Previously, she served as senior sports psychologist for the United States Olympic Committee (USOC), preparing the country’s top athletes for dominant performances at two Winter Olympics and one Summer Olympics.

Polar explorer, TED speaker, and record-breaking long-distance skier Ben Saunders fuses the spirit of adventure with impressive technical ingenuity. He has five North Pole expeditions under his belt and is best known for leading one of the most ambitious expeditions in a century. Humble and self-effacing, he is an explorer of limits and his message is one of inspiration, empowerment, and boundless potential. He explores the dichotomy between ideas and action and urges audiences to consider carefully how to spend the “tiny amount of time we each have on this planet.”

A decorated veteran of the sea, air, land, and outer space, Captain Chris Cassidy is among the leaders of an exclusive and distinguished group of accomplished military astronauts who have made an impact on and beyond this world. Recognized for his leadership and achievements as a United States Navy SEAL and a NASA astronaut, CAPT Cassidy’s various military deployments and spaceflight missions provided the catalysts for an action-packed career where he made the most of every opportunity presented to him, even in challenging and high-stakes environments.

Described by Dr. Brené Brown as one of her “leadership heroes and a total badass,” U.S. Air Force retired Colonel, DeDe Halfhill is a proven leader who draws from 25 years of command experience and as a senior advisor to the military’s highest-ranking officials to provide a real-world perspective on the power of embracing humanness and vulnerability in leadership. Twice deployed to Iraq, DeDe’s sought-after leadership insights are grounded in personal experiences commanding and advising organizations through challenging environments — often when lives were at risk and there were no easy answers. As a senior advisor to the U.S. Secretary of Defense and the Chairman of the Joint Chiefs of Staff, DeDe was a trusted influence in developing solutions to the military’s most-pressing issues. She also served as the military’s lead spokesperson responsible for implementing plans supporting the Department of Defense’s global communications strategy.

Scott spent almost ten years as a nightclub promoter in New York City before leaving to volunteer on a hospital ship off the coast of Liberia, West Africa, as a volunteer photo journalist. Returning home to New York City two years later, he founded the non-profit organization, charity: water, in 2006. Turning his full attention to the global water crisis and the world’s 663 million people without clean water to drink, he created public installations and innovative online fundraising platforms to spread international awareness of the issue.

Erik Weihenmayer is a world-class adventurer, the first blind man to summit Mount Everest, and one of only 150 mountaineers to climb the Seven Summits. His latest and most demanding adventure is kayaking the 277 miles of the Grand Canyon. One of the most exciting and well-known athletes in the world, he never let his lack of vision interfere with his quality of life. Weihenmayer’s feats have earned him incredible press coverage and dozens of awards. He is also the author of two books and addresses leadership, teamwork, overcoming adversity, motivation, and inspiration.