Jessica O. Matthews is the Founder & CEO of Uncharted, an award-winning energy and data technology company that develops infrastructure solutions for communities, facilities, and Internet of Things. The company was founded by Jessica when she was only 22 years old. Jessica’s research and career centers around the intersection of disruptive technology, renewable energy, human behavior, and the psychology of self-actualization. A dual citizen of Nigeria & the U.S., Jessica has a degree in Psychology and Economics from Harvard University, an MBA from Harvard Business School, and is listed on over 10 patents and patents pending—including her first invention of the SOCCKET, an energy generating soccer ball, at the age of 19.

Part journalist, part historian, and all shrewd political observer, Ronald (Ron) Brownstein explains the complexities of American politics with lucid precision. As a CNN Senior Political Analyst, Senior Editor for the Atlantic, and Contributing Editor for National Journal, he produces sharp analysis on politics, policy, the electorate, media, healthcare, energy, the press' impact on Americans, and the range of issues informed by his strong sense of American political and national history. Brownstein provides an insider’s look into politics and the media and has twice been a finalist for the Pulitzer Prize. He is also the author of seven best-selling books, and his articles on politics, public policy, and culture have appeared in myriad of major publications and on many broadcast news outlets.

With a medical, scientific, and philanthropic career that spans more than 30 years, Dr. Sue Desmond-Hellmann has devoted her life to improving the human condition through innovation. Most recently, she was the CEO of the Bill & Melinda Gates Foundation, leading the organization’s vision for a world where every person has the opportunity to live a healthy, productive life. She was formerly the first female chancellor of University of California at San Francisco and spent 14 years at biotech firm Genentech, leading the development of a number of breakthrough medicines. An innovator and leader in life sciences, Dr. Desmond-Hellmann’s diverse training as an oncologist, scientist, and business executive leads to her endless curiosity about the world and her desire to change it for the better. In speeches, she shares her unique insights not only on revolutionizing global health, but also on effective and innovative leadership. Using lessons-learned as a trailblazing female leader of one of the world’s largest philanthropies, Dr. Desmond-Hellmann inspires audiences with her unparalleled perspective on how to foster an environment of collaboration and relentless innovation to drive disruptive solutions that make an impact.

Ramez Naam is a former Microsoft executive, entrepreneur, inventor, and the Energy Co-Chair at Singularity University. Ramez spent 13 years at Microsoft, where he led teams working on artificial intelligence, big data, and internet search. His software has touched the lives of more than a billion people. He holds more than 20 patents—including several as co-inventor with Bill Gates. Dynamic and personable, Naam speaks around the world, captivating audiences as he illustrates “what disruption looks like” and shares the eight strategies incumbents should draw on to keep the pace of change.

Dr. Fauci has served the country with a relentless pursuit of discovery and innovation. Serving as the director of the National Institute of Allergy and Infectious Diseases (NIAID) for 38 years and being a public servant for more than 50 years, Dr. Fauci oversaw an extensive research portfolio devoted to the prevention, diagnosis, and treatment of infectious and immune-mediated diseases. As the key advisor to 7 Presidents and their administrations, Dr. Fauci lead medical and public health preparedness and treatments against emerging infectious disease threats, including HIV/AIDS, pandemic influenza, Ebola, Zika, and COVID-19.

Jon Wellinghoff is the Chief Regulatory Officer of Voltus, the world’s leading platform for Distributed Energy Resources (DER). An internationally-recognized energy expert, he known for his forward-thinking approach to energy policy and his track record of moving the needle on the clean energy revolution. Jon draws on his decades experience in energy, policy, and business to discuss future opportunities in the fields of wind power, solar power, electric cars, and the development of smart cities, as well as implementing innovative business strategies and corporate cultures.

Described as America’s most widely recognized medical expert after Dr. Anthony Fauci, Dr. Vin Gupta, MD, MPA is a tech visionary who operates at the heart of disruption to develop solutions to the most-complex challenges in commerce, communication, healthcare, and society — now, and in the future. Close to two decades of experience as a renowned health policy expert and clinician have led Dr. Gupta to his current role as chief medical officer, Amazon Pharmacy, where he spearheads cutting-edge programs that are leading us into the interdependent futures of healthcare and technology. A uniquely public-facing figure keeping the world in the know about what’s happening now and next, Dr. Gupta’s forward-looking insights inspire leaders and their organizations to embrace change, think outside the box to break new ground, and create new inroads to innovation and success.

Few people have had the immense impact that Meghan O’Sullivan has had at the highest levels of geopolitics. She is a globally respected geopolitical expert who has advised the nation’s highest-ranking leaders — from President George W. Bush to Secretary of State Antony Blinken — on some of the most-complex challenges in international affairs. Currently, Dr. O’Sullivan is the Director of the Belfer Center for Science and International Affairs and the Jeane Kirkpatrick Professor of the Practice of International Affairs at Harvard University’s Kennedy School. There, she leads 300 scholars, practitioners, and staff as they advance the boundaries of international relations, security, technology, science, energy, and the environment. The Belfer Center has consistently been ranked as the world’s top academic think tank.

Widely respected as an innovator in unlocking high performance in teams and individuals, Dr. Wendy Borlabi possesses expert-level understanding of the mental aspects of peak performance and works alongside the world’s top athletes to help them reframe their mindsets to reach their full potential. She is the director of performance and mental health for the Chicago Bulls where her mindset-centered philosophy to mastering your field is embedded in the team’s success and prevalent at all levels of the organization and its culture. A leading sports psychologists and performance coach, Dr. Borlabi is also an independent consultant with the NBA and is the founder of performance psychology firm Borlabi Consulting, through which she advises organizations in any industry on teamwork, elevating mental toughness, and inspiring unwavering confidence in their teams. Previously, she served as senior sports psychologist for the United States Olympic Committee (USOC), preparing the country’s top athletes for dominant performances at two Winter Olympics and one Summer Olympics.

Erik Peterson sits at the intersection of global economics, geopolitical changes, and future trends. His riveting presentations are eye-opening glimpses into how we can and should address some of the most challenging global issues of our time. He maps the key long-range trends transforming the opportunities and risks and traces the simultaneous and significant global shifts in the areas of population, resources, technology, economy, security, and geopolitics. He untangles these complex trends for audiences and examines the real-world implications—both present and future.

A leading thinker on global energy, power systems, and innovation, Robert Bryce is one of America’s most prominent energy journalists. He's renowned for his analysis of industrial trends and the future of energy in his five books, where he skillfully explains the scale, physics, and math behind our energy and power systems while exposing the myriad myths about energy.

Amy Harder is executive editor of Cipher by Breakthrough Energy. Amy is one of the top national energy and climate change reporters in the country, having built up a reputation of being a uniquely balanced and influential journalist with respect across the spectrum. She joined Breakthrough Energy in early 2021 to help launch Cipher, a publication covering the opportunities and challenges of the energy transition.