For almost 50 years, The Second City has been the training ground for a host of famous alumni including John Belushi, Mike Myers, Gilda Radner, Tina Fey, Steve Carell, Stephen Colbert, and countless stars of stage and screen. Second City Communications works with corporate groups to create a fun, interactive and unconventional approach to training and entertainment.

MakerHealth CEO, Anna Young, works from a fundamental belief that, with the right tools, everyday people can use their ingenuity to create devices that heal. Applying years of global experience with the Maker Movement, Anna brings prototyping tools and makerspaces into hospitals enhance the natural problem-solving abilities of clinicians and patients. Anna is the co-founder of MakerNurse, an RWJF sponsored program to support inventive, frontline nurses. Anna’s roots come from MIT as researcher in the Little Devices Lab and lecturer in the Institute for Medical Engineering and Science. In 2015, Anna was recognized by LinkedIn as a "Top Health Innovator Under 35" and in 2016 received Fast Company’s "Most Creative People in Business."

Geeta Nayyar, MD, MBA, is a globally recognized chief medical officer, technologist, and bestselling author who helps leaders leverage a human approach to innovation, including rapid advances in AI, to achieve better health and business outcomes. A widely sought-after speaker and author of the Wall Street Journal and USA Today bestseller “Dead Wrong: Diagnosing and Treating Healthcare’s Misinformation Illness,” Dr. G has appeared on CNBC, CNN, CBS, and other prominent media outlets. She has served as chief medical officer for Salesforce and AT&T, among other executive roles. She currently serves on the board of the American Telemedicine Association and as an advisor to the American Medical Association. A rheumatologist, Dr. G earned her medical degree at the University of Miami Miller School of Medicine, where she was admitted into an accelerated program at age 17, and her MBA at The George Washington University School of Business.

Kien Vuu MD (Doctor V) is a human and organizational longevity and performance expert and a doctor who’s found a better way. By achieving the Thrive State, Doctor V has not only reversed his own chronic diseases, but has achieved peak mental, physical, and emotional performance, and has biologically aged backwards. Doctor V combines enthusiasm, energy, and entertainment to his keynotes and workshops. The Thrive State is an energy - a lifeforce - that activates the biology of human potential, and can be cultivated and harnessed in any individual or organization through a simple actionable framework. His mission is to empower people and organizations to reclaim their health and serve with fulfillment, abundance, and purpose.

JOSHUA HARE is Chief Sciences Officer, Senior Associate Dean for Experimental and Cellular Therapeutics, Director of the Interdisciplinary Stem Cell Institute (ISCI), and Louis Lemberg Professor of Medicine at the University of Miami Miller School of Medicine. Dr. Hare is a practicing cardiologist with board certifications in cardiology and advanced heart failure and cardiac transplantation. During his research career, he has pioneered the use of allogenic adult cell therapy for multiple disease areas. Under his leadership, and in partnership with many faculty across the University of Miami campus, ISCI developed cell-based therapy programs in cancer biology, cardiology, aging, neonatology, skin diseases, bone diseases, neurologic diseases, ophthalmology, and a program devoted to the ethics of stem cell therapy.

Haley Barbour is the former governor of Mississippi and the former chairman of the Republican Governor’s Association. He also served as chairman of the Republican National Committee, leading the GOP to gain control of Congress for the first time in 40 years. POLITICO calls him “the most powerful Republican in politics.” He was also widely praised for his handling of both the Gulf Oil Spill and Hurricane Katrina. One of the Republican Party’s top political strategists, Barbour addresses elections, politics, Republican strategy, the economy, and other hot political topics.

Former Senator John Breaux (D-LA), the deputy minority whip until his retirement, held key Senate committee positions. He was a senior member of the Finance Committee, chairman of the Subcommittee on Social Security and Family Policy, and Co-Chairman of the President's Tax Reform Commission. He also held positions on the Subcommittees of Health Care and Taxation and IRS Oversight. Breaux addresses politics, health care, energy, bipartisanship, and lessons learned from Hurricane Katrina and the oil spill.

Tripp Crosby is a comedic host, inspirational speaker, and filmmaker who is at this very moment writing about himself in the third person. It’s very, very possible that you’ve seen his most popular comedy sketch called “A Conference Call in Real Life”. This video is one of, if not the most popular workplace related comedy sketches of all time and possibly the only YouTube video to ever go viral twice: Once when Tripp first created it in 2013 and again in 2020 when the painful experience of participating in conference calls became an even more relatable topic.

Susan Sher, the former chief of staff to First Lady Michelle Obama and Chicago’s first female corporation counsel, is a long-time friend of the Obamas. Originally hired as the President’s associate counsel, Sher was part of his health care reform team before moving to the East Wing. There she helped promote the new legislation and the First Lady’s anti-obesity campaign. Previously, Sher was the vice president for legal and governmental affairs of the University of Chicago Hospitals for more than a decade. She addresses health care, the White House, and women in leadership.

John Cleese is one of Britain's best-known actors, writers and comedians. Famous primarily for his comic efforts, such as the television series Fawlty Towers and the exploits of the Monty Python troupe, he has also become a well-respected actor in his own right and has co-written books on psychiatry entitled Families And How to Survive Them and Life And How to Survive It.

After a debilitating car crash sent Brian Boyle to the ICU, his future looked bleak. This athlete beat the odds and had one of the greatest comebacks in sports history. His message will inspire and amaze any audience.

Jim Carroll is recognized as the world’s leading futurist, trends and innovation experts, with a massive global blue-chip client list. Over the last 30 years, more than 2 million people have shared his insight at his events. Jim’s global client list gives him a front-row seat to the high-velocity change that is occurring as disruption comes to take hold of every industry and every organization. With that insight, and the customized research that he undertakes for every engagement, he helps to transform growth-oriented organizations into high-velocity innovation heroes! Jim provides high energy keynotes for audiences of 50 to 5,000, as well as intimate, customized strategic planning sessions for CEO/CxO, board, and senior management meetings. He has researched key innovation success factors for dozens of organizations and industries including life sciences, health care, insurance, automotive, manufacturing, agriculture, technology, education, government, consumer products, retail, banking and countless others. He has been invited in by NASA (twice) to share his insight on the future of the space industry; by Disney, to advise on new strategies for creativity and innovation; by the PGA of America for his thoughts on how to accelerate the golf industry; by Pfizer for insight on the future of medical science; by the World Bank for his thoughts on opportunities for economic development; and by the Wall Street Journal for his perspective on disruptive trends. Among countless others... Jim Carroll is an author, with numerous books including Now What?, Think Big, Start Small, Scale Fast;, Surviving the Information Age, The Future Belongs To Those Who Are Fast, Ready, Set, Done: and What I Learned From Frogs in Texas.