With a medical, scientific, and philanthropic career that spans more than 30 years, Dr. Sue Desmond-Hellmann has devoted her life to improving the human condition through innovation. Most recently, she was the CEO of the Bill & Melinda Gates Foundation, leading the organization’s vision for a world where every person has the opportunity to live a healthy, productive life. She was formerly the first female chancellor of University of California at San Francisco and spent 14 years at biotech firm Genentech, leading the development of a number of breakthrough medicines. An innovator and leader in life sciences, Dr. Desmond-Hellmann’s diverse training as an oncologist, scientist, and business executive leads to her endless curiosity about the world and her desire to change it for the better. In speeches, she shares her unique insights not only on revolutionizing global health, but also on effective and innovative leadership. Using lessons-learned as a trailblazing female leader of one of the world’s largest philanthropies, Dr. Desmond-Hellmann inspires audiences with her unparalleled perspective on how to foster an environment of collaboration and relentless innovation to drive disruptive solutions that make an impact.

Jenny Radcliffe is a “people hacker” — or a mix of shrewd behavioral scientist, master negotiator, and actor. Known for talking her way into high-security banks and even the Tower of London, Jenny is a world-renowned coach, consultant, and speaker who brings something different to meetings focused on culture, social intelligence, sales, negotiation, and interpersonal relationships. A regular keynote at major security events — including Infosec, Rant, DISA, Nordic IT Security, ICS2, Trend Micro, Cisco, NTT, Bright talk, and Cyber Security Week — and a multiple-times TEDx contributor, Radcliffe has been a guest expert on security, scams and social engineering for various television and radio shows as well as online media. She helps clients understand how to better read people and social cues, use subtle tactics of persuasion, open up avenues of conversation previously shut, and understand and shield against their own vulnerabilities.

A presidential-level communicator with more than three decades experience as a national security official, Beth Sanner is among the most influential voices at the highest levels of American intelligence. As the senior-most analyst for the entire Intelligence Community (IC), she was a trusted adviser to the President of the United States on our nation’s most important intelligence matters – first as the Office of the Director of National Intelligence’s director of the President’s Daily Brief and later as the Deputy Director of National Intelligence for Mission Integration. Having served in several leadership, staff, policy, and analytic positions in the IC, Sanner has briefed four Presidents and also advised vice presidents, congressional and cabinet officials, and foreign partners; her acumen is highly sought after by our nation’s decisionmakers and organizations across various industries. Sanner uniquely immerses audiences in her talks —making them feel as though they are our nation’s leaders being briefed on hot-button developments with the potential to reshape our world.

Sue M. Gordon is the former Principal Deputy Director of National Intelligence (PDDNI) – the country’s number two ranking intelligence official. As the fifth PDDNI, she co-led the Office of the Director of National Intelligence and oversaw the entire Intelligence Community, comprised of over a dozen agencies that collect information on threats against the United States. In particular, Gordon’s transformative leadership focused on integrating intelligence across the organization, expanding outreach and partnerships, driving innovation, and advancing diversity and inclusion throughout the Community. With nearly four decades of legendary and dedicated service, Gordon has led at every level of the Intelligence Community with roles spanning numerous organizations and disciplines – drawing on this experience to inspire audiences to challenge the status quo, adapt to changing environments, and apply innovation to their business.

Amy Harder is executive editor of Cipher by Breakthrough Energy. Amy is one of the top national energy and climate change reporters in the country, having built up a reputation of being a uniquely balanced and influential journalist with respect across the spectrum. She joined Breakthrough Energy in early 2021 to help launch Cipher, a publication covering the opportunities and challenges of the energy transition.

Marga Hoek is a member of Thinkers50, she is that rare combination: a true visionary on sustainable business and capital and a successful, innovative business leader who understands and applies the commercial realities of business. Operating at the highest level with ministers and presidents, Marga is a global voice for G20, G7 Climate Change and Cop 23 and a regular contributor for prestigious, global media like Forbes Magazine, Fortune and The Huffington Post. Her latest book The Trillion Dollar Shift, on the business opportunities of the Sustainable Development Goals, received an international, gold medal.

Sophia Kianni is an Iranian-American environmentalist studying climate science and public policy at Stanford University. She is the founder and executive director of Climate Cardinals, an international nonprofit with 8,000 volunteers in 40+ countries working to translate climate information into over 100 languages. She represents the U.S as the youngest member on the inaugural United Nations Youth Advisory Group on Climate Change. Sophia’s work has been featured in news outlets including Forbes, CNN, Business Insider, BBC, NPR, ELLE, TIME Magazine, The Guardian, NBC, and even on the front page of The Washington Post. She was previously a fellow with PBS NewsHour and has written for news outlets such as MTV News, Cosmopolitan, Refinery 29, and Teen Vogue. She is a prolific public speaker and has spoken at universities across the country including Columbia University, UC Berkeley, Johns Hopkins, Cambridge University, and Harvard University. She gave her debut TED Talk as the closing speaker at the inaugural TED Countdown Conference. She has been named VICE Media's youngest Human of the Year, a National Geographic Young Explorer, and one of Teen Vogue's 21 under 21.

Sandra Taylor is CEO of Sustainable Business International LLC, a consulting business that assists clients at various stages of environmental sustainability and corporate social responsibility in the food and beverage sectors. Previously Sandra was a senior executive with Starbucks Coffee Company in Seattle, where she led global responsibility and sustainability in coffee and cocoa supply chains. She is the author of The Business of Sustainable Wine, published in July 2017. Sandra received her BA from Colorado Women’s college, JD from Boston University School of Law and MBA program from the Bordeaux School of Management/Kedge Business School in France.

Kathy Varol is an expert at driving profit with purpose. Kathy created the Global Purpose (corporate social responsibility) strategy for adidas, a 22 billion dollar global company. Now Kathy helps her clients use purpose to stand out in a competitive environment, attract the best talent, gain consumer loyalty, and fully harness the innovative brainpower of their employees (innovation that keeps them miles ahead of the competition). She shares her deep knowledge and “how-to” with clients, so they can skip the hard lessons and go straight to strategies that work. Kathy has 20 years of experience across brand marketing, strategy, and impact, working at established brands like adidas, MillerCoors, and Microsoft. Through her experience, Kathy has developed a repeatable 4-step process to become a purpose-led brand: The Brand Purpose Model. When businesses embed purpose into the heart of their strategy, they don’t just disrupt their industry. They also bring humanity into the workplace, shape the future, and impact the world.

Barrier-breaker, transformational leader, a force to be reckoned with — these are just some of the words to describe Daphne E. Jones, an accomplished and seasoned Fortune 50 executive whose forward-looking vision played a key role in unlocking growth within various multinational corporations. Through the course of her illustrious 30-year career, she held executive roles at IBM, Johnson & Johnson, Hospira, Inc. (now Pfizer) — where she shattered the ‘concrete’ ceiling by becoming the first woman and first person of color to report to the Chairman of the Board and CEO, and General Electric, where she became the highest-ranking African American woman in GE IT. Jones is widely regarded as a power player in her field and draws upon her extensive experience using digital technologies strategically, entrepreneurially, and globally to advise organizations in every industry on the way forward for their businesses.

Trevor Williams served as Chief Economist at Lloyds Bank for over a decade. Now an author, academic and consultant, he analyses the key trends and policies that shape the economy and markets. From energy and climate to how companies use their data to understand the wider economy, he brings clarity and relevance to an often complex and abstract field.

Anthony Foxx is the Chief Policy Officer at Lyft who formerly served as the 17th United States Secretary of Transportation and as mayor of Charlotte, North Carolina. As Secretary of Transportation, he led an agency with more than 55,000 employees and a budget of $70 billion. A digital cities innovator known as "the Great Connector" for his work in government, he discusses the American transportation system, digital cities, innovation, and coalition building.