With a medical, scientific, and philanthropic career that spans more than 30 years, Dr. Sue Desmond-Hellmann has devoted her life to improving the human condition through innovation. Most recently, she was the CEO of the Bill & Melinda Gates Foundation, leading the organization’s vision for a world where every person has the opportunity to live a healthy, productive life. She was formerly the first female chancellor of University of California at San Francisco and spent 14 years at biotech firm Genentech, leading the development of a number of breakthrough medicines. An innovator and leader in life sciences, Dr. Desmond-Hellmann’s diverse training as an oncologist, scientist, and business executive leads to her endless curiosity about the world and her desire to change it for the better. In speeches, she shares her unique insights not only on revolutionizing global health, but also on effective and innovative leadership. Using lessons-learned as a trailblazing female leader of one of the world’s largest philanthropies, Dr. Desmond-Hellmann inspires audiences with her unparalleled perspective on how to foster an environment of collaboration and relentless innovation to drive disruptive solutions that make an impact.

Amy Walter is the publisher and editor-in-chief of the Cook Political Report with Amy Walter, where she provides analysis of the issues, trends, and events that shape the political environment. A contributor to the PBS NewsHour, she provides weekly political analysis for the popular “Politics Monday” segment. She is also a regular Sunday panelist on NBC’s Meet the Press and CNN’s Inside Politics, and appears frequently on Special Report with Bret Baier on Fox News Channel. From 2017 until early 2021, Walter was the host of the weekly nationally syndicated program “Politics with Amy Walter” on The Takeaway from WNYC and PRX. She is the former political director at ABC News and known as one of the best political journalists in Washington. For more than 20 years, she has built a reputation as an accurate, objective, and insightful analyst with unparalleled access to campaign insiders and decision-makers. Her analysis has earned her numerous accolades, including the Washington Post’s Crystal Ball Award and being named one of the top 50 journalists by Washingtonian. Walter addresses the electoral process, congressional culture, and the Washington political scene.

Nicolle Wallace is host of Deadline: White House, chief political analyst for MSNBC and NBC News, a best-selling author, and the former White House director of communications under President George W. Bush. Her West Wing colleague, presidential political adviser Mark McKinnon, called her a “rare talent in politics.” Funny and charming, she shares insights on the biggest issues of the day paired with stories from her time in the White House and on the campaign trail. Wallace is a master storyteller as she offers audiences the rundown they need to stay in the know.

A.B. Stoddard is a columnist for the political news and opinion publication The Bulwark, and a contributor and guest host for SiriusXM’s POTUS channel. Prior to The Bulwark, she was associate editor and columnist for the political news site and polling data aggregator RealClearPolitics, as well as associate editor and columnist for The Hill newspaper. Her column with The Hill won first place Dateline Awards from the Society of Professional Journalists. She has published articles in the Boston Globe, Congressional Quarterly, and The Federal Paper and is known for her commentary on the 2008 U.S. presidential election. Stoddard also regularly appears on Fox's Special Report with Bret Baier and CNN's New Day as well as other shows on Fox News Channel, Fox Business Network, CNN, and MSNBC. She addresses politics and elections.

Amy Harder is executive editor of Cipher by Breakthrough Energy. Amy is one of the top national energy and climate change reporters in the country, having built up a reputation of being a uniquely balanced and influential journalist with respect across the spectrum. She joined Breakthrough Energy in early 2021 to help launch Cipher, a publication covering the opportunities and challenges of the energy transition.

Marga Hoek is a member of Thinkers50, she is that rare combination: a true visionary on sustainable business and capital and a successful, innovative business leader who understands and applies the commercial realities of business. Operating at the highest level with ministers and presidents, Marga is a global voice for G20, G7 Climate Change and Cop 23 and a regular contributor for prestigious, global media like Forbes Magazine, Fortune and The Huffington Post. Her latest book The Trillion Dollar Shift, on the business opportunities of the Sustainable Development Goals, received an international, gold medal.

Sophia Kianni is an Iranian-American environmentalist studying climate science and public policy at Stanford University. She is the founder and executive director of Climate Cardinals, an international nonprofit with 8,000 volunteers in 40+ countries working to translate climate information into over 100 languages. She represents the U.S as the youngest member on the inaugural United Nations Youth Advisory Group on Climate Change. Sophia’s work has been featured in news outlets including Forbes, CNN, Business Insider, BBC, NPR, ELLE, TIME Magazine, The Guardian, NBC, and even on the front page of The Washington Post. She was previously a fellow with PBS NewsHour and has written for news outlets such as MTV News, Cosmopolitan, Refinery 29, and Teen Vogue. She is a prolific public speaker and has spoken at universities across the country including Columbia University, UC Berkeley, Johns Hopkins, Cambridge University, and Harvard University. She gave her debut TED Talk as the closing speaker at the inaugural TED Countdown Conference. She has been named VICE Media's youngest Human of the Year, a National Geographic Young Explorer, and one of Teen Vogue's 21 under 21.

Sandra Taylor is CEO of Sustainable Business International LLC, a consulting business that assists clients at various stages of environmental sustainability and corporate social responsibility in the food and beverage sectors. Previously Sandra was a senior executive with Starbucks Coffee Company in Seattle, where she led global responsibility and sustainability in coffee and cocoa supply chains. She is the author of The Business of Sustainable Wine, published in July 2017. Sandra received her BA from Colorado Women’s college, JD from Boston University School of Law and MBA program from the Bordeaux School of Management/Kedge Business School in France.

Kathy Varol is an expert at driving profit with purpose. Kathy created the Global Purpose (corporate social responsibility) strategy for adidas, a 22 billion dollar global company. Now Kathy helps her clients use purpose to stand out in a competitive environment, attract the best talent, gain consumer loyalty, and fully harness the innovative brainpower of their employees (innovation that keeps them miles ahead of the competition). She shares her deep knowledge and “how-to” with clients, so they can skip the hard lessons and go straight to strategies that work. Kathy has 20 years of experience across brand marketing, strategy, and impact, working at established brands like adidas, MillerCoors, and Microsoft. Through her experience, Kathy has developed a repeatable 4-step process to become a purpose-led brand: The Brand Purpose Model. When businesses embed purpose into the heart of their strategy, they don’t just disrupt their industry. They also bring humanity into the workplace, shape the future, and impact the world.

Ana Navarro is a well-known Republican strategist and a political analyst for CNN, CNN en Español, Telemundo, and co-host of ABC's The View. Tampa Bay Times called her “a sought-after voice in Republican politics and an adviser for any presidential hopeful,” saying, “with confidants Jeb Bush and Marco Rubio she is poised to play a big role in the GOP response to immigration reform and Hispanic outreach.” Respected on both sides of the aisle for her straight shooting and candor, Navarro is frequently called upon for her spot-on commentary. She is in touch with the political issues people are talking about, and in presentations, she discusses the latest hot button issues in politics, giving audiences an insider’s view of the upcoming elections and a roadmap for where the country is headed.

Margaret Brennan is the moderator of CBS News' Face the Nation with Margaret Brennan and the network's senior foreign affairs correspondent based in Washington, DC. Brennan has reported on politics, international affairs, foreign relations, the economy, and global markets since she joined CBS News in 2012 and was named the White House and senior foreign affairs in 2017. Prior to joining CBS News, Brennan spent a decade covering global finance, anchoring a weekday show on Bloomberg Television called "InBusiness with Margaret Brennan."

Few possess Sarah Isgur’s deep level of insights and expertise when it comes to explaining transformative events in law and politics, and how society is being reshaped around them. Regarded among the nation’s most reputable and in-the-know political commentators, Isgur served as the director of the Office of Public Affairs at the U.S. Justice department from 2017-2018. She has a been a spark plug in politics for the entirety of her career, working high-profile campaign roles for several political heavyweights, including Mitt Romney and Carly Fiorina. Currently, she is a senior editor for The Dispatch, as well host of the publication’s legal podcast, “Advisory Opinions” and a professor at George Washington University’s School of Media and Public Affairs.