With a medical, scientific, and philanthropic career that spans more than 30 years, Dr. Sue Desmond-Hellmann has devoted her life to improving the human condition through innovation. Most recently, she was the CEO of the Bill & Melinda Gates Foundation, leading the organization’s vision for a world where every person has the opportunity to live a healthy, productive life. She was formerly the first female chancellor of University of California at San Francisco and spent 14 years at biotech firm Genentech, leading the development of a number of breakthrough medicines. An innovator and leader in life sciences, Dr. Desmond-Hellmann’s diverse training as an oncologist, scientist, and business executive leads to her endless curiosity about the world and her desire to change it for the better. In speeches, she shares her unique insights not only on revolutionizing global health, but also on effective and innovative leadership. Using lessons-learned as a trailblazing female leader of one of the world’s largest philanthropies, Dr. Desmond-Hellmann inspires audiences with her unparalleled perspective on how to foster an environment of collaboration and relentless innovation to drive disruptive solutions that make an impact.

A 21-year veteran of the United States Air Force, Colonel Nicole Malachowski (USAF, Ret.) wanted to fly military jets from the moment she saw them at her first air show when she was five years old. She achieved that goal – and then some. A leader, a combat veteran, the first woman pilot on the Thunderbirds Air Demonstration Squadron, an instructor, a White House Fellow, and an inductee into the Women in Aviation International Pioneer Hall of Fame, Nicole’s Air Force career exceeded her wildest dreams.

An adventurer, record-setter, and boundary-breaker, Darcy Gaechter is best known as the first woman - and member of the first team - to kayak the Amazon River from source to sea. The journey required her crew to paddle over 4,000 miles across the widest part of South America, a voyage that took 148 days to complete. She is also the author of The Kayaker’s Guide to Ecuador and Amazon Woman, an adventure memoir detailing her Amazon River expedition and the life challenges she faced to get there – the rights of which have been purchased to turn her story into a movie. Gaechter inspires audiences with her personal journey of overcoming obstacles and making the impossible possible – sharing useful tactics to take on even the most daunting of challenges and demonstrating how a strong belief in yourself and in your goal are key ingredients to any success.

Debbie Sterling is the Founder and CEO of GoldieBlox, an award winning company on a mission to ‐"disrupt the pink aisle" with toys, games, and media for girls. Debbie is an engineer, entrepreneur, and one of the leaders in the movement toward getting girls interested in science, technology, engineering, and math. She was named TIME Magazine’s "Person of the Moment,” Business Insider’s "30 Women Who Are Changing the World,” and was recently added to Fortune Magazine’s prestigious “40 Under 40” list. In early 2015, Debbie was inducted as a Presidential Ambassador for Global Entrepreneurship and honored by the National Women’s History Museum with a “Living Legacy” Award for her work to empower girls around the world.

Jenn Lim is the CEO and Chief Happiness Officer of Delivering Happiness, a company that she and Tony Hsieh (CEO of Zappos) co-created in 2010 to inspire happiness in work, community and everyday life. In 2005, she created the first Culture Book for Zappos – now on its 7th edition – and has produced them ever since. In 2009, Zappos was sold to Amazon.com in a deal valued at $1.2 billion on the day of closing, and in 2011, Zappos was #6 on Fortune’s “100 Best Companies to Work For” list. The Culture Book has become a global symbol of how companies can successfully create cultures based on happiness and be profitable at the same time.

Elizabeth Gore is the Entrepreneur-in-Residence at Dell, where she drives initiatives that support Dell’s goals around helping small and medium businesses scale and prosper, fueling the expansion of global entrepreneurship. She is Chairman of the Board for Alice, the world's first AI tool for entrepreneurs, which provides founders with services to help them scale and succeed. Finally, she chairs the United Nations Foundation’s Global Entrepreneurs Council and builds global partnerships that positively affect the UN’s most pressing humanitarian issues.

Jane Chen is the co-founder and CEO of Embrace, a social enterprise that aims to help the 15 million premature and low birth-weight babies born every year, through a low-cost infant warmer. The Embrace infant warmer costs about 1% of a traditional incubator and is estimated to have helped over 250,000 babies to date. Most recently, Embrace Innovations launched a new line of baby products for the US market called Little Lotus Baby, which uses NASA inspired technology to keep babies at the perfect temperature so they can sleep better. They are using buy-one, give-one model: for every product sold, a baby is helped in a developing country by the Embrace infant warmer.

Jessica Kriegel (KREE-GL) is a workplace culture strategist. She is a Doctor of Leadership & Management and Fortune 100 Thought Leader. She is a dynamic speaker, consultant, Co-Active coach, and is author of Unfairly Labeled: How Your Workplace Can Benefit from Ditching Generational Stereotypes and upcoming book, The Culture Equation. For 15+ years, Jessica has been guiding global, national, Fortune 100 and other organizations on how to create intentional cultures that power your strategy and accelerate performance.

With an exceptional track record of sparking brilliant leaders and turning soft skills into hard results, Jackie Insinger combines relatability and humor with her data-driven, results-focused approach to teamwork and leadership. Equal parts captivating and motivating, Jackie inspires immediate action that leads to inevitable transformation. By leveraging the latest research in neuroscience and positive psychology, Jackie designs simple, actionable strategies that individuals can use right away to spark their team’s brilliance - taking them beyond “good to great” and transforming them from “great to extraordinary.” As a best-selling author with degrees from Duke and Harvard and a certification in Neuroscience for Business from MIT, Jackie’s ideas have been a game-changer for thousands of people and businesses worldwide.