With a medical, scientific, and philanthropic career that spans more than 30 years, Dr. Sue Desmond-Hellmann has devoted her life to improving the human condition through innovation. Most recently, she was the CEO of the Bill & Melinda Gates Foundation, leading the organization’s vision for a world where every person has the opportunity to live a healthy, productive life. She was formerly the first female chancellor of University of California at San Francisco and spent 14 years at biotech firm Genentech, leading the development of a number of breakthrough medicines. An innovator and leader in life sciences, Dr. Desmond-Hellmann’s diverse training as an oncologist, scientist, and business executive leads to her endless curiosity about the world and her desire to change it for the better. In speeches, she shares her unique insights not only on revolutionizing global health, but also on effective and innovative leadership. Using lessons-learned as a trailblazing female leader of one of the world’s largest philanthropies, Dr. Desmond-Hellmann inspires audiences with her unparalleled perspective on how to foster an environment of collaboration and relentless innovation to drive disruptive solutions that make an impact.

Katie Ledecky is a 10-time Olympic Medalist (seven Gold, three Silver) and 21-time World Championship Gold Medalist, the most for any female swimmer. She has broken 14 World Records and 37 American Records in her career. Katie was the most decorated female athlete at both Tokyo and Rio Games and had the most decorated single Olympics performance ever by a U.S. female athlete in Rio. Katie’s success has earned her USA Swimming’s Golden Goggles Award as Female Swimmer of the Year an unprecedented eight times. A recent graduate of Stanford University, Katie is passionate about the importance of education, especially STEM and leadership programs for girls. Katie went home with more hardware at the Tokyo 2020 Olympics - two gold medals and two silver medals, making her the most decorated female swimmer in individual events of all time. She also made history by winning gold at the first ever 1500m women’s event.

Described by the media as everything from “Superwoman undercover” to “The Pied Piper of potential,” Sarah Robb O’Hagan is an executive, activist, entrepreneur, and founder of Extreme Living — a content platform designed to help individuals, teams, and organizations play to their highest potential. Currently, she is the CEO of EXOS, the leading performance coaching company that gets people ready for the moments that matter most in their work, sport, and daily lives. EXOS clients range from NFL players and Olympians to corporate executives, military personnel, and every day people looking to manage stressors and thrive in the new normal of fast-paced modern-day life. Drawing on her decades experience at some of the world's most influential brands, she shares practical takeaways including how to make failure your fuel, discover your most competitive playing field, get out of line rather than always following conventional wisdom, and bring out the “extreme" in others.

Dedicated to creating the conscious workplace for tomorrow, Virginia “Ginny” Clarke is a seasoned executive recruiter who has advised at the highest levels of corporate America for decades. A proven expert in driving diverse leadership, she is the former director of executive recruiting at Google, where she led the company’s diversity, non-tech recruiting, and leadership internal mobility teams – finding and hiring senior leaders across the company. She also built a scaled internal mobility program for Google’s senior leaders and designed much of the infrastructure that supports their executive recruiting function today. In speeches, Clarke draws on her unparalleled experience assessing thousands of executives inside corporate C-Suites and boardrooms to bring a unique, holistic five-dimensional approach to true leadership that is essential now more than ever. She delivers “no-holds-barred” discussions on the root causes that lead to a lack of diversity in organizations, and provides the integrated solutions that anyone can use to affect change.

Poppy Jamie is an entrepreneur, influencer, and rising star in the happiness, mental health, and mindfulness space. She is the founder of the mental wellbeing company and app Happy Not Perfect – a source to better brain health. A deeply personal project combining behavioral scientific research, inspiration from her mother, and real life-experience, she created Happy Not Perfect to inspire and empower people to take control of their mental health through products, services, and experiences. As organizations worldwide grapple with how to manage the growing mental health crisis, Poppy provides a clear path to overcoming uncertainty, fears of rejection, anxiety, and burnout to find peace with the past and create a happier, healthier future. She is also author of the anticipated book Happy Not Perfect.

Crystal Washington, CSP works with organizations that want to leverage technology to increase profits and productivity! As a technology strategist and certified futurist, Crystal takes complex social media, app, and web topics, and makes them easy to understand and accessible for everyday people. Crystal’s clients comprise Fortune 500 companies including Google, Microsoft, and GE and as a sought-after keynote speaker, she has entertained and educated audiences around the globe. She has appeared in numerous publications including Entrepreneur, Bloomberg Businessweek, and Forbes and is regularly called on by major television networks as a tech expert. Crystal is the author of the books One Tech Action and The Social Media Why.

Amy Harder is executive editor of Cipher by Breakthrough Energy. Amy is one of the top national energy and climate change reporters in the country, having built up a reputation of being a uniquely balanced and influential journalist with respect across the spectrum. She joined Breakthrough Energy in early 2021 to help launch Cipher, a publication covering the opportunities and challenges of the energy transition.

A 21-year veteran of the United States Air Force, Colonel Nicole Malachowski (USAF, Ret.) wanted to fly military jets from the moment she saw them at her first air show when she was five years old. She achieved that goal – and then some. A leader, a combat veteran, the first woman pilot on the Thunderbirds Air Demonstration Squadron, an instructor, a White House Fellow, and an inductee into the Women in Aviation International Pioneer Hall of Fame, Nicole’s Air Force career exceeded her wildest dreams.

Marga Hoek is a member of Thinkers50, she is that rare combination: a true visionary on sustainable business and capital and a successful, innovative business leader who understands and applies the commercial realities of business. Operating at the highest level with ministers and presidents, Marga is a global voice for G20, G7 Climate Change and Cop 23 and a regular contributor for prestigious, global media like Forbes Magazine, Fortune and The Huffington Post. Her latest book The Trillion Dollar Shift, on the business opportunities of the Sustainable Development Goals, received an international, gold medal.

When entrepreneur and former top brand executive Michelle Cordeiro Grant set out to start her own company, she did so with the mission to create a brand, experience, and community that empowers women. What followed was Lively, the ultra-successful activewear-inspired lingerie brand that she built into an industry leader and disruptor in less than 10 years. Introducing "Leisurée" to the world, Cordeiro Grant identified opportunities to turn the apparel market on its head and redefined approaches for leading an organization to success.

Clara is the Founder and Executive Chair of Hearsay Corporation, which provides software to help companies securely manage and measure their presence across Facebook, Twitter, and other social media. In 2007, Clara created the first business application on Facebook with her Faceconnector application, which integrates Facebook and Salesforce CRM.

Sophia Kianni is an Iranian-American environmentalist studying climate science and public policy at Stanford University. She is the founder and executive director of Climate Cardinals, an international nonprofit with 8,000 volunteers in 40+ countries working to translate climate information into over 100 languages. She represents the U.S as the youngest member on the inaugural United Nations Youth Advisory Group on Climate Change. Sophia’s work has been featured in news outlets including Forbes, CNN, Business Insider, BBC, NPR, ELLE, TIME Magazine, The Guardian, NBC, and even on the front page of The Washington Post. She was previously a fellow with PBS NewsHour and has written for news outlets such as MTV News, Cosmopolitan, Refinery 29, and Teen Vogue. She is a prolific public speaker and has spoken at universities across the country including Columbia University, UC Berkeley, Johns Hopkins, Cambridge University, and Harvard University. She gave her debut TED Talk as the closing speaker at the inaugural TED Countdown Conference. She has been named VICE Media's youngest Human of the Year, a National Geographic Young Explorer, and one of Teen Vogue's 21 under 21.