With a medical, scientific, and philanthropic career that spans more than 30 years, Dr. Sue Desmond-Hellmann has devoted her life to improving the human condition through innovation. Most recently, she was the CEO of the Bill & Melinda Gates Foundation, leading the organization’s vision for a world where every person has the opportunity to live a healthy, productive life. She was formerly the first female chancellor of University of California at San Francisco and spent 14 years at biotech firm Genentech, leading the development of a number of breakthrough medicines. An innovator and leader in life sciences, Dr. Desmond-Hellmann’s diverse training as an oncologist, scientist, and business executive leads to her endless curiosity about the world and her desire to change it for the better. In speeches, she shares her unique insights not only on revolutionizing global health, but also on effective and innovative leadership. Using lessons-learned as a trailblazing female leader of one of the world’s largest philanthropies, Dr. Desmond-Hellmann inspires audiences with her unparalleled perspective on how to foster an environment of collaboration and relentless innovation to drive disruptive solutions that make an impact.

Michael (Mike) Steep is the founder and former executive director of Stanford Engineering School's Center for Disruptive Technology and Digital Cities and the former senior vice president of global business operations at innovation mega-hub, PARC Xerox. He draws on first-hand experience and anecdotes from time spent with the biggest names in Silicon Valley to instruct audiences on how to get ahead of disruptive innovation. Viewing new technology as opportunity, Mike highlights the importance of allowing innovation to trump company culture and legacies—and not the other way around.

Amy Harder is executive editor of Cipher by Breakthrough Energy. Amy is one of the top national energy and climate change reporters in the country, having built up a reputation of being a uniquely balanced and influential journalist with respect across the spectrum. She joined Breakthrough Energy in early 2021 to help launch Cipher, a publication covering the opportunities and challenges of the energy transition.

Colin Coggins and Garrett Brown are agents of change who are known for their surprising and entertaining approaches to purpose-driven leadership and igniting culture shifts that reposition organizations to scale growth and make a profound impact in their teams, and with their customers. At the foundation of Colin and Garrett’s philosophy is the idea that the most successful leaders and teams are the ones who are able to evolve transactional encounters into transformational experiences where connections are made, solutions are created, and value is felt. After decades of collective experience as sales professionals, leaders, and executives, Colin and Garrett’s paths crossed at enterprise software company Bitium, where they played key roles in growing the business from relative obscurity to a prominent acquisition by Google. They now serve as adjunct professors of entrepreneurship at the University of Southern California’s Marshall School of Business, where they teach the hugely popular, first-of-its-kind class, “Sales Mindset for Entrepreneurs.”

An award-winning innovator and disruptor, Reggie Fils-Aimé is a proven expert on transforming companies, re-vitalizing brands, and reshaping industries to solve daunting challenges and achieve ‘the impossible.’ Most recently, he was the president and chief operating officer of Nintendo of America – the first American and African-American to hold this position. Revered by business leaders and gaming fans alike, Fils-Aimé helped bring Nintendo’s greatest successes – including the Nintendo DS, the Wii, the Nintendo 3DS, Wii U, and the Nintendo Switch – to the global marketplace. Using his personal story as an example, he shares with audiences his principles for effective and innovative leadership, including defining a vision, courage in decision-making, and “irrefutable integrity.”

The first African-American woman to hold the top policing job in Seattle, Washington, Carmen Best served with the Seattle Police Department for 28 years. In 2018, Best was promoted to Chief of Police, a job she called “a dream of a lifetime.” Best quickly began efforts to diversify the police force, which had long been less diverse than the city, recruiting more than 40 new officers of color. Chief Best speaks on diversity, inclusion, and leadership lessons-learned guiding a police department during times of crisis.

Laila Ali is a world-class athlete, fitness & nutrition expert, TV host, cooking enthusiast, founder of the Laila Ali Lifestyle Brand and mother of two. The daughter of late beloved global icon and humanitarian, Muhammad Ali, she is a four-time undefeated boxing world champion, whose stellar record includes 24 wins (21 of which were "knockouts") and zero losses. Laila is heralded as the most successful female in the history of women’s boxing.

Deepa Purushothaman (per-shot-a-man) is a corporate truth teller and inclusion visionary who, throughout her illustrious career, challenged and redefined the status quo of leadership, success, and power on her incredible journey of breaking glass ceilings and advancing the workplace for all people. For more than two decades, Deepa held various high-level executive leadership roles at Deloitte, eventually becoming the first Indian American woman and one of the youngest people ever to make partner at the internationally renowned global services firm, and breaking new ground for subsequent generations to follow in her footsteps.

Kien Vuu MD (Doctor V) is a human and organizational longevity and performance expert and a doctor who’s found a better way. By achieving the Thrive State, Doctor V has not only reversed his own chronic diseases, but has achieved peak mental, physical, and emotional performance, and has biologically aged backwards. Doctor V combines enthusiasm, energy, and entertainment to his keynotes and workshops. The Thrive State is an energy - a lifeforce - that activates the biology of human potential, and can be cultivated and harnessed in any individual or organization through a simple actionable framework. His mission is to empower people and organizations to reclaim their health and serve with fulfillment, abundance, and purpose.

Alex Banayan is an entrepreneur and author of The Third Door, which chronicles his five-year quest tracking down Bill Gates, Lady Gaga, Warren Buffett, Maya Angelou, Steven Spielberg, Jane Goodall, Steve Wozniak, Jessica Alba, Larry King, and dozens more of the world’s most successful people. An acclaimed keynote speaker, Banayan has presented the Third Door framework to business conferences and corporate leadership teams around the world, including Apple, Google, Nike, IBM, Snapchat, Salesforce, and Disney. Banayan’s keynotes have had far-reaching effects, acting as the catalyst for a new way of thinking. The Third Door framework has helped individuals discover unconventional routes to achieve their biggest dreams and has aided Fortune 500 companies to take new approaches to sales, marketing, and exponential growth.

Ramez Naam is a former Microsoft executive, entrepreneur, inventor, and the Energy Co-Chair at Singularity University. Ramez spent 13 years at Microsoft, where he led teams working on artificial intelligence, big data, and internet search. His software has touched the lives of more than a billion people. He holds more than 20 patents—including several as co-inventor with Bill Gates. Dynamic and personable, Naam speaks around the world, captivating audiences as he illustrates “what disruption looks like” and shares the eight strategies incumbents should draw on to keep the pace of change.

Four-time Olympic gold medalist, Janet Evans, has been recognized as the best female distance swimmer in United States history. Calling on her experience as a world-record setting swimmer, Janet executes motivational speeches for top companies in varying fields including: Technology, Healthcare, Real Estate, Telecommunications, Apparel, Banking, Insurance, Trade Associations, packaged goods, non profits and many others. With her easy style and grace on a podium, Janet has helped veteran salesman and senior executives alike!